Norco vs Vicodin comparison. Norco and Vicodin are common narcotic pain killers made of two active ingredients, acetaminophen and hydrocodone. The levels of these two ingredients differs in each drug; Norco contains higher levels of hydrocodone while Vicodin contains higher levels of. Norco (hydrocodone / acetaminophen) has two medicines to treat moderate to moderately severe pain. The combination is more effective than either drug alone. I was prescribed Vicodin 500mg and now my Dr. put me on Vicoprofen for my pain. I noticed, the two medications have the same key ingredient- Hydrocodone. what makes one better then the other? thankyou. Compare Vicodin vs. Vicoprofen, which is better for uses like: Pain, Breakthrough Pain and Severe Pain. Compare head-to-head ratings, side effects, warnings, dosages, interactions and patient reviews. Patients rated Vicoprofen 3.6/5 over Vicodin 2.8/5 in overall satisfaction. Oxycodone and hydrocodone are prescription pain medications. Both can treat short-term pain caused by an injury or surgery. They may also be used to treat pain that is chronic, or long-term. You can experience withdrawal symptoms if you suddenly stop taking Ibudone (Hydrocodone / Ibuprofen). Not a good choice if you have high blood pressure or kidney, liver, or stomach problems. Constipation, dizziness, drowsiness, and nausea can commonly occur. yes, the amount of narcotic (hydrocodone) is the same when comparing vicoprofen and vicodin es. the only difference is, like you stated, the ibuprofen which has an anti-inflammatory affect Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Kent on vicoprofen vs vicodin: I would have to ask better for what purpose ?. Vicodin and Percocet are opioid narcotic medications. Morphine also belongs to this class. The U.S. Drug Enforcement Administration classifies opioids as Schedule 2 drugs. Hydrocodone and Vicodin are drugs that are given to alleviate pain. Pain as a fifth vital sign is another important assessment among humans. Pain can be a sign of impending deadly occurrences, such as, chest pain in heart attacks.